TM Flow

TM Flow Intended Use:

  • Measurement of Ankle Brachial Indices for the screening of Peripheral Artery Disease.
  • Measurement of the Galvanic Skin response related to the sudomotor function.
  • Mathematical Analysis of the Photoplethysmography for assessing:- The autonomic nervous system via Heart Rate Variability Analysis at the rest and during the Ewing Tests
    – The Endothelial function via the Photoplethysmography (PTG) Analysis.

TM Flow Main Markers


  • Arterial stiffness and Ankle Brachial Indices from the Volume plethysmography analysis.
  • Endothelial FunctionPatented markers from mathematical analysis of the photoplethysmography spectral analysis. (Off label use).


  • Sudomotor Function Markers.
  • Heart rate variability Analysis  (HRV).
  • Cardiac Autonomic Reflex Tests:
    –  Valsalva Ratio,
    ​-  E/I Ratio ,
    –  K30/15 Ratio and
    ​-  Systolic Pressure Response to Standing.

TM Flow Clinical Validation

  • PTG Spectral Analysis Markers to:​

    – The gold standard of Insulin resistance assessment.
    – The Coronary angiography.
    – Vascular blood tests (CRP and fibrinogen).
  • Cardiometabolic Score to the Oral Glucose Tolerance Test (OGTT).
  • Sudomotor markers to the:
    – Small fiber Neuropathy Symptoms.
    – Microvascular disease (retinopathy).